Vanilla is derived from orchids in the genus Vanilla. Traditionally, vanilla has been used as a food flavoring as well as for scent. Vanilla planifolia, native to Mexico, is the predominant species throughout the world. Vanilla supply is threatened, and many vanilla-flavored products are not made with natural vanilla.
Vanilla has few reported medicinal uses. There is limited evidence that vanilla has antibacterial, antifungal, anticancer, antioxidant, insect repellant, food preservative, and radioprotective properties. It may be useful in treating sickle cell anemia. The scent of vanilla has been shown to have calming effects on newborns.
Some vanilla products have been contaminated with bacteria, as well as coumarin, a compound in plants that prevents blood clotting. Allergic reactions have been reported. Vanilla may also affect the taste of breast milk, which may influence food preference in breastfed adults.
Brunton, PA and Hussain, A. The erosive effect of herbal tea on dental enamel. J Dent 2001;29(8):517-520. View Abstract
Camps, N, Dominguez, A, Company, M, et al. A foodborne outbreak of Salmonella infection due to overproduction of egg-containing foods for a festival. Epidemiol.Infect. 2005;133(5):817-822. View Abstract
Eccles, R, Lancashire, B, and Tolley, NS. Experimental studies on nasal sensation of airflow. Acta Otolaryngol 1987;103(3-4):303-306. View Abstract
Ferguson, JE and Beck, MH. Contact sensitivity to vanilla in a lip salve. Contact Dermatitis 1995;33(5):352. View Abstract
Garcia AF, Cabal C, Losada J, et al. In vivo action of Vanillin on delay time determined by magnetic relaxation. Hemoglobin 2005;29(3):181-187. View Abstract
Goubet N, Strasbaugh K, and Chesney J. Familiarity breeds content? Soothing effect of a familiar odor on full-term newborns. J Dev.Behav.Pediatr 2007;28(3):189-194. View Abstract
Haller, R, Rummel, C, Henneberg, S, et al. The influence of early experience with vanillin on food preference later in life. Chem Senses 1999;24(4):465-467. View Abstract
Kanny, G, Hatahet, R, Moneret-Vautrin, DA, et al. Allergy and intolerance to flavouring agents in atopic dermatitis in young children. Allerg.Immunol (Paris) 1994;26(6):204-210. View Abstract
Kistemann, T, Dangendorf, F, Krizek, L, et al. GIS-supported investigation of a nosocomial Salmonella outbreak. Int J Hyg Environ.Health 2000;203(2):117-126. View Abstract
Kumar, A, Rawlings, RD, and Beaman, DC. The mystery ingredients: sweeteners, flavorings, dyes, and preservatives in analgesic/antipyretic, antihistamine/decongestant, cough and cold, antidiarrheal, and liquid theophylline preparations. Pediatrics 1993;91(5):927-933. View Abstract
Mazza, DS, O'Sullivan, M, and Grieco, MH. HIV-1 infection complicated by food allergy and allergic gastroenteritis: a case report. Ann Allergy 1991;66(5):436-440. View Abstract
Mennella, JA. Mother's milk: a medium for early flavor experiences. J Hum Lact 1995;11(1):39-45. View Abstract
Nnamani IN, Joshi GS, Danso-Danquah R, et al. Pyridyl derivatives of benzaldehyde as potential antisickling agents. Chem Biodivers 2008;5(9):1762-1769. View Abstract
Odink, J, Korthals, H, and Knijff, JH. Simultaneous determination of the major acidic metabolites of catecholamines and serotonin in urine by liquid chromatography with electrochemical detection after a one-step sample clean-up on Sephadex G-10; influence of vanilla and banana ingestion. J Chromatogr 2-26-1988;424(2):273-283. View Abstract
Rattaz C, Goubet N, and Bullinger A. The calming effect of a familiar odor on full-term newborns. J Dev.Behav.Pediatr 2005;26(2):86-92. View Abstract