- Scullcap (Scutellaria lateriflora) is native to the United States.
- Traditionally, scullcap has been used as a relaxant, and it is well-known for its antispasmodic actions. Native Americans traditionally used scullcap extracts as sedatives and diuretics.
- Although early evidence suggests that it may have antidepressant or anti-anxiety properties, there is not enough available evidence in humans to support the use of scullcap for any medical condition.