- Mullein has been used in natural medicine for centuries and is among the oldest known medicinal plants. Mullein was brought to North America from Europe by settlers and was commonly used as a remedy for cough and diarrhea. It is found along roadsides, fields and barren areas in the United States.
- Traditionally, a poultice made from mullein leaves has been applied to the skin to treat ulcers and hemorrhoids. Mullein is typically used for inflammation in various areas of the body. The most commonly reported use is for respiratory tract conditions such as bronchitis and asthma, and also for ear pain associated with earaches. The proposed mechanism of action is by reducing the amount of mucous formation and as an expectorant.
- Currently, there are no available scientific studies (animal or human) that examine the efficacy of mullein alone. As of July 2006, the U. S. Food and Drug Administration (FDA) reported that mullein flowers (Verbascum phlomoides L. or V. thapsiforme Schrad.) are likely safe for use as natural flavoring substances and natural adjuvants in food in small amounts. However, mullein is categorized as a food additive for which a petition has been filed and a regulation issued. Further research is required before any recommendations can be made.