- Both marshmallow (Althaea officinalis) leaf and root are used in commercial preparations. Herbal formulations are made from either the dried root or leaf (unpeeled or peeled). The actual mucilaginous content of the commercial product may vary according to the time of collection.
- There is a lack of available clinical trials assessing marshmallow alone for any specific health condition. Medicinal uses of marshmallow are supported mostly by traditional use and laboratory research. Limited human evidence is available studying the effects of marshmallow-containing combination products in skin conditions.
- Although clinically unproven, marshmallow may interfere with the absorption of medications taken by mouth. Therefore, ingestion of marshmallow several hours before or after other agents may be warranted.
- Marshmallow is generally regarded as safe. However, the potential for marshmallow to cause allergic reactions or low blood sugar has been noted anecdotally.
- Althaea extract has been used to make pills. Marshmallow has also been used as an aid to X-ray exams of the esophagus.