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Kinetin

Kinetin

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Contents

  • Kinetin is a chemical analogue of cytokinins, a class of plant hormones that promotes cell division. Kinetin is found in both plants and animals.
  • Scientific studies have investigated whether kinetin might help lower side effects associated with cataract surgery, aid in the treatment of Meniere's disease or decrease eye blood pressure. Currently, there is not enough scientific evidence to support any of these uses.
  • Adunka O, Moustaklis E, Weber A, et al. Labyrinth anesthesia--a forgotten but practical treatment option in Meniere's disease. ORL J Otorhinolaryngol.Relat Spec. 2003;65(2):84-90.
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  • Barciszewski J, Mielcarek M, Stobiecki M, et al. Identification of 6-furfuryladenine (kinetin) in human urine. Biochem Biophys Res Commun. 12-9-2000;279(1):69-73.
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  • Barciszewski J, Siboska GE, Pedersen BO, et al. Furfural, a precursor of the cytokinin hormone kinetin, and base propenals are formed by hydroxyl radical damage of DNA. Biochem Biophys Res Commun. 9-18-1997;238(2):317-319.
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  • Glaser DA, Rogers C. Topical and systemic therapies for the aging face. Facial.Plast.Surg Clin North Am 2001;9(2):189-96, vii.
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  • Griffaut B, Bos R, Maurizis JC, et al. Cytotoxic effects of kinetin riboside on mouse, human and plant tumour cells. Int J Biol Macromol. 2004;34(4):271-275.
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  • Hipkiss AR. On the "struggle between chemistry and biology during aging"--implications for DNA repair, apoptosis and proteolysis, and a novel route of intervention. Biogerontology. 2001;2(3):173-178. . View Abstract
  • Honma Y, Ishii Y. Differentiation of human myeloid leukemia cells by plant redifferentiation-inducing hormones. Leuk.Lymphoma 2002;43(9):1729-1735.
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  • Hsiao G, Shen MY, Lin KH, et al. Inhibitory activity of kinetin on free radical formation of activated platelets in vitro and on thrombus formation in vivo. Eur J Pharmacol 4-4-2003;465(3):281-287.
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  • Ishii Y, Hori Y, Sakai S, et al. Control of differentiation and apoptosis of human myeloid leukemia cells by cytokinins and cytokinin nucleosides, plant redifferentiation-inducing hormones. Cell Growth Differ. 2002;13(1):19-26.
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  • Ishii Y, Kasukabe T, Honma Y. Immediate up-regulation of the calcium-binding protein S100P and its involvement in the cytokinin-induced differentiation of human myeloid leukemia cells. Biochim.Biophys Acta 9-10-2005;1745(2):156-165.
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  • Ishii Y, Sakai S, Honma Y. Cytokinin-induced differentiation of human myeloid leukemia HL-60 cells is associated with the formation of nucleotides, but not with incorporation into DNA or RNA. Biochim.Biophys Acta 12-7-2003;1643(1-3):11-24.
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  • Kligman D. Cosmeceuticals. Dermatol Clin 2000;18(4):609-615.
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  • Olsen A, Siboska GE, Clark B F, et al. N(6)-Furfuryladenine, kinetin, protects against Fenton reaction-mediated oxidative damage to DNA. Biochem Biophys Res Commun. 11-19-1999;265(2):499-502.
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  • Sheu JR, Hsiao G, Shen MY, et al. Inhibitory mechanisms of kinetin, a plant growth-promoting hormone, in platelet aggregation. Platelets. 2003;14(3):189-196.
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  • Slaugenhaupt SA, Mull J, Leyne M, et al. Rescue of a human mRNA splicing defect by the plant cytokinin kinetin. Hum.Mol.Genet. 2-15-2004;13(4):429-436.
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