Hydrangea (Hydrangea arborescens L.)

Natural Standard developed the above evidence-based information based on a thorough systematic review of the available scientific articles. For comprehensive information about alternative and complementary therapies on the professional level, go to . Selected references are listed below.

• Avenel-Audran M, Hausen BM, le Sellin J, et al. Allergic contact dermatitis from hydrangea--is it so rare? Contact Dermatitis 2000;43(4):189-191.
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• Bruynzeel DP. Contact dermatitis from hydrangea. Contact Dermatitis 1991;24(1):78.
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• Bruynzeel DP, Hausen BM. Allergic contact dermatitis to hydrangea. Contact Dermatitis 1987;16(3):181.
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• Bruynzeel DP. Allergic contact dermatitis to hydrangea. Contact Dermatitis 1986;14(2):128.
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• De Rooij J, Bruynzeel DP, Rustemeyer T. Occupational allergic contact dermatitis from hydrangea. Contact Dermatitis 2006;54(1):65-66.
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• Ishih A, Miyase T, Terada M. Comparison of antimalarial activity of the alkaloidal fraction of Hydrangea macrophylla var. Otaksa leaves with the hot-water extract in ICR mice infected with Plasmodium yoelii 17 XL. Phytother Res. 2003;17(6):633-639.
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• Kikuchi M, Kakuda R, Kikuchi M, et al. Three new glycosides from the leaves of Hydrangea macrophylla subsp. serrata (THUNB.) MAKINO. Chem Pharm Bull (Tokyo) 2008;56(4):610-611.
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• Kuligowski ME, Chang A, Leemreize JH. Allergic contact hand dermatitis from hydrangea: report of a 10th case. Contact Dermatitis 1992;26(4):269-270.
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• Matsuda H, Wang Q, Matsuhira K, et al. Inhibitory effects of thunberginols A and B isolated from Hydrangeae Dulcis Folium on mRNA expression of cytokines and on activation of activator protein-1 in RBL-2H3 cells. Phytomedicine. 2008;15(3):177-184.
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• Meijer P, Coenraads PJ, Hausen BM. Allergic contact dermatitis from hydrangea. Contact Dermatitis 1990;23(1):59-60.
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• Rademaker M. Occupational contact dermatitis to hydrangea. Australas J Dermatol. 2003;44(3):220-221.
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• Tsuji Y, Denda S, Soma T, et al. A potential suppressor of TGF-beta delays catagen progression in hair follicles. J Investig Dermatol Symp Proc. 2003;8(1):65-68.
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• Yang Q, Gong ZZ. Purification and characterization of an ethylene-induced antifungal protein from leaves of guilder rose (Hydrangea macrophylla). Protein Expr Purif. 2002;24(1):76-82.
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• Yoshida K, Ito D, Shinkai Y, et al. Change of color and components in sepals of chameleon hydrangea during maturation and senescence. Phytochemistry 4-16-2008;
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• Zhang H, Matsuda H, Kumahara A, et al. New type of anti-diabetic compounds from the processed leaves of Hydrangea macrophylla var. thunbergii (Hydrangeae Dulcis Folium). Bioorg Med Chem Lett. 9-1-2007;17(17):4972-4976.
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