- Gossypol is a pigment that is most commonly produced by the stem, seeds, and roots of the cotton plant. Gossypol was first identified as an infertility agent when studies were conducted in China to explain extremely low birth rates in a particular geographic region. The phenomenon was attributed to the use of crude cottonseed oil for cooking; further investigation revealed that the antifertility agent was gossypol.
- Gossypol may cause infertility in men, potentially making it a promising alternative to surgical vasectomy. In early research, gossypol shows some evidence of benefit as a treatment for endometriosis and certain cancers, but further research is necessary.
- At low doses and for short durations, gossypol is well tolerated. However, its use is limited by the fact that it may cause potassium depletion and infertility.
- In traditional medicine practices, gossypol has been used to treat nasal polyps, uterine fibroids, and other types of cancer. A tea of fresh or roasted seeds has been used to treat bronchitis, diarrhea, dysentery, and hemorrhage. Cottonseed oil was used by early American slaves for abortion.
- Further research is needed to determine if lower doses, possibly in combination with other therapies, may be effective and safe.
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ingredients
Gossypol
Contents
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