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Cotton

ingredients

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  • Gossypium hirsutum is a cotton species native to Central America and the Caribbean. After being domesticated in the United States, this cotton species now provides over 90% of commercial cotton worldwide.
  • The dried root bark of cotton contains gossypol. This compound may cause abortion-inducing effects. Gossypol may be isolated more easily from the bark. Other parts of the cotton plant have limited gossypol content.
  • Cotton has a history of use for breastfeeding, contraception, diarrhea, female reproduction, fever, headache, pregnancy, nausea, and various other applications.
  1. Ajaiyeoba, E. O., Falade, C. O., Fawole, O. I., Akinboye, D. O., Gbotosho, G. O., Bolaji, O. M., Ashidi, J. S., Abiodun, O. O., Osowole, O. S., Itiola, O. A., Oladepo, O., Sowunmi, A., and Oduola, A. M. Efficacy of herbal remedies used by herbalists in Oyo State Nigeria for treatment of Plasmodium falciparum infections--a survey and an observation. Afr.J Med Med Sci 2004;33(2):115-119. View Abstract
  2. Ankrah, N. A., Nyarko, A. K., Addo, P. G., Ofosuhene, M., Dzokoto, C., Marley, E., Addae, M. M., and Ekuban, F. A. Evaluation of efficacy and safety of a herbal medicine used for the treatment of malaria. Phytother.Res 2003;17(6):697-701. View Abstract
  3. Annan, K. and Houghton, P. J. Antibacterial, antioxidant and fibroblast growth stimulation of aqueous extracts of Ficus asperifolia Miq. and Gossypium arboreum L., wound-healing plants of Ghana. J Ethnopharmacol. 9-2-2008;119(1):141-144. View Abstract
  4. Conway, G. A. and Slocumb, J. C. Plants used as abortifacients and emmenagogues by Spanish New Mexicans. J Ethnopharmacol. 1979;1(3):241-261. View Abstract
  5. Flack, M. R., Pyle, R. G., Mullen, N. M., Lorenzo, B., Wu, Y. W., Knazek, R. A., Nisula, B. C., and Reidenberg, M. M. Oral gossypol in the treatment of metastatic adrenal cancer. J Clin Endocrinol.Metab 1993;76(4):1019-1024. View Abstract
  6. Herman, D. L. and Smith, F. H. Effect of bound gossypol on the absorption of iron by rats. J Nutr 1973;103(6):882-889. View Abstract
  7. Leipelt, M., Warnecke, D., Zahringer, U., Ott, C., Muller, F., Hube, B., and Heinz, E. Glucosylceramide synthases, a gene family responsible for the biosynthesis of glucosphingolipids in animals, plants, and fungi. J Biol.Chem 9-7-2001;276(36):33621-33629. View Abstract
  8. Liu, G. Z., Ch'iu-Hinton, K., Cao, J. A., Zhu, C. X., and Li, B. Y. Effects of K salt or a potassium blocker on gossypol-related hypokalemia. Contraception 1988;37(2):111-117. View Abstract
  9. Liu, G. Z., Lyle, K. C., and Cao, J. Clinical trial of gossypol as a male contraceptive drug. Part I. Efficacy study. Fertil.Steril. 1987;48(3):459-461. View Abstract
  10. Nakayama, T., Shimazaki, K., Ono, J., Ohsato, K., and Yamaura, A. [Intracranial foreign body granuloma caused by fine cotton fibers: a case report]. No Shinkei Geka 1994;22(11):1081-1084. View Abstract
  11. Oberto, G., Bauza, E., Berghi, A., Portolan, F., Botto, J. M., Peyronel, D., Dal, Farra C., and Domloge, N. Cotton honeydew (Gossypium hirsutum L.) extract offers very interesting properties for hair cosmetics and care products. Drugs Exp.Clin Res 2005;31(4):131-140. View Abstract
  12. Qian, S. Z. and Wang, Z. G. Gossypol: a potential antifertility agent for males. Annu.Rev.Pharmacol.Toxicol. 1984;24:329-360. View Abstract
  13. Qian, S. Z., Jing, G. W., Wu, X. Y., Xu, Y., Li, Y. Q., and Zhou, Z. H. Gossypol related hypokalemia. Clinicopharmacologic studies. Chin Med J (Engl.) 1980;93(7):477-482. View Abstract
  14. Sepehri, H., Roghani, M., and Houdebine, M. L. Oral administration of pectin-rich plant extract enhances C3 and C4 complement concentration in woman colostrum. Reprod.Nutr Dev. 1998;38(3):255-260. View Abstract
  15. Sunilkumar, G., Campbell, L. M., Puckhaber, L., Stipanovic, R. D., and Rathore, K. S. Engineering cottonseed for use in human nutrition by tissue-specific reduction of toxic gossypol. Proc.Natl.Acad.Sci U.S.A 11-28-2006;103(48):18054-18059. View Abstract