- Cissus quadrangularis is a vine native to Africa, Southeast Asia, and India. Historically, Cissus quadrangularis was used for bone health, pain relief, and stomach conditions.
- Traditionally, parts of the Cissus plant have been mashed, roasted, juiced, pulped, or cooked before application. In modern times, Cissus quadrangularis has been taken as a powder or capsule.
- Cissus quadrangularis has been studied for its potential to treat osteoporosis and obesity. Additional research on these topics is needed.