Beta-alanine is a beta-amino acid that differs structurally from most amino acids found in the diet. In the body, beta-alanine forms part of the structure of vitamin B5, carnosine, and dihydrouracil. In the diet, beta-alanine is found mostly in meat, such as chicken, beef, pork, and fish.
Beta-alanine is thought to enhance exercise performance, mainly for activities that require power or strength, such as sprinting or weight lifting. Human studies have shown that beta-alanine may increase time to exhaustion, peak power during running, and an increase in weight and number of repetitions for the bench press. However, more research is needed.
Amounts of beta-alanine over 10 milligrams per kilogram of body weight may cause a feeling of "pins and needles." This feeling may go away after a few weeks of continuous use.
Deldicque L and Francaux M. Functional food for exercise performance: fact or foe? Curr Opin.Clin Nutr Metab Care 2008;11(6):774-781. View Abstract
Derave W, Ozdemir MS, Harris RC, et al. beta-Alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters. J Appl.Physiol 2007;103(5):1736-1743. View Abstract
Dunnett M and Harris RC. Influence of oral beta-alanine and L-histidine supplementation on the carnosine content of the gluteus medius. Equine Vet.J Suppl 1999;30:499-504. View Abstract
Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino.Acids 2007;32(2):225-233. View Abstract
Hoffman JR, Ratamess NA, Faigenbaum AD, at al. Short-duration beta-alanine supplementation increases training volume and reduces subjective feelings of fatigue in college football players. Nutr Res 2008;28(1):31-35. View Abstract
Hoffman J, Ratamess NA, Ross R, et al. Beta-alanine and the hormonal response to exercise. Int J Sports Med 2008;29(12):952-958. View Abstract
Kendrick IP, Harris RC, Kim HJ, et al. The effects of 10 weeks of resistance training combined with beta-alanine supplementation on whole body strength, force production, muscular endurance and body composition. Amino.Acids 2008;34(4):547-554. View Abstract
Kendrick IP, Kim HJ, Harris RC, et al. The effect of 4 weeks beta-alanine supplementation and isokinetic training on carnosine concentrations in type I and II human skeletal muscle fibres. Eur J Appl.Physiol 2009;106(1):131-138. View Abstract
Stellingwerff T, Boit MK, and Res PT. Nutritional strategies to optimize training and racing in middle-distance athletes. J Sports Sci 2007;25 Suppl 1:S17-S28. View Abstract
Stout JR, Cramer JT, Mielke M, et al. Effects of twenty-eight days of beta-alanine and creatine monohydrate supplementation on the physical working capacity at neuromuscular fatigue threshold. J Strength Cond.Res 2006;20(4):928-931. View Abstract
Stout JR, Cramer JT, Zoeller RF, et al. Effects of beta-alanine supplementation on the onset of neuromuscular fatigue and ventilatory threshold in women. Amino.Acids 2007;32(3):381-386. View Abstract
Stout JR, Graves BS, Smith AE, et al. The effect of beta-alanine supplementation on neuromuscular fatigue in elderly (55-92 Years): a double-blind randomized study. J Int Soc Sports Nutr 2008;5:21. View Abstract
Tipton KD, Jeukendrup AE, and Hespel P. Nutrition for the sprinter. J Sports Sci 2007;25 Suppl 1:S5-15. View Abstract
Van Gennip AH, Abeling NG, Vreken P, et al. Inborn errors of pyrimidine degradation: clinical, biochemical and molecular aspects. J Inherit.Metab Dis 1997;20(2):203-213. View Abstract
Van Thienen R, Van Proeyen K, Vanden Eynde B, et al. Beta-alanine improves sprint performance in endurance cycling. Med Sci Sports Exerc 2009;41(4):898-903. View Abstract